ADEM: Age at Onset and Neuropsychological Outcome
نویسندگان
چکیده
منابع مشابه
Does early age at brain insult predict worse outcome? Neuropsychological implications.
OBJECTIVE Traditionally early brain insult (EBI) has been argued to have better outcome than later injury, consistent with the notion that the young brain is flexible and able to reorganize. This view was investigated by comparing neurobehavioral outcomes of children sustaining EBI at different developmental stages (gestation to late childhood). METHODS One hundred and sixty four children who...
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In 1957 Landau and Kleffner described an unusual childhood disorder which they termed ‘syndrome of acquired aphasia with convulsive disorder’, in which language regresses after a period of normal development and seizures develop. Children with this disorder typically have severe receptive language difficulties and often are at first thought to be deaf. However, pure-tone audiometry shows normal...
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Age at onset in Huntington's disease (HD) is variable and is influenced by parental sex, paternal age, and genetic background. Several recent models have tried to explain this variable expressivity by invoking parental imprinting and related aspects of epigenetic inheritance. Some of these mechanisms may result in variable DNA methylation at or near the HD gene. We show here that methylation at...
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ژورنال
عنوان ژورنال: Pediatric Neurology Briefs
سال: 2004
ISSN: 2166-6482,1043-3155
DOI: 10.15844/pedneurbriefs-18-9-2